Dorsal root ganglion (DRG) neuronal model (Amir, Devor 2003)

The model shows that an electrically excitable soma is not necessary for spike through-conduction in the t-shaped geometry of a dorsal root ganglion neuron axon. Electrical excitability of the soma is required, however, for soma spike invasion. See papers for details and more.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Myelinated neuron; Dorsal Root Ganglion (DRG) cell

Currents: I Na,t; I K

Model Concept(s): Activity Patterns; Detailed Neuronal Models; Axonal Action Potentials; Action Potentials

Simulation Environment: NEURON

Implementer(s): Amir, Ron [ronamir at]


Amir R, Devor M. (2003). Electrical excitability of the soma of sensory neurons is required for spike invasion of the soma, but not for through-conduction. Biophysical journal. 84 [PubMed]

Amir R, Devor M. (2003). Extra spike formation in sensory neurons and the disruption of afferent spike patterning. Biophysical journal. 84 [PubMed]

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.