Sodium dynamics drives the generation of slow oscillations postulated to underly NMDA-evoked bursting activity.
Model Type: Neuron or other electrically excitable cell; Electrogenic pump
Cell Type(s): Substantia nigra pars compacta DA cell
Currents: Na/K pump
Receptors: NMDA
Model Concept(s): Activity Patterns; Oscillations; Sodium pump
Simulation Environment: NEURON
Implementer(s): Canavier, CC
References:
Canavier CC. (1999). Sodium dynamics underlying burst firing and putative mechanisms for the regulation of the firing pattern in midbrain dopamine neurons: a computational approach. Journal of computational neuroscience. 6 [PubMed]