"In a recent set of modeling studies we have developed a stochastic threshold model of auditory nerve response to single biphasic electrical pulses (Bruce et al., 1999c) and moderate rate (less than 800 pulses per second) pulse trains (Bruce et al., 1999a). In this article we derive an analytical approximation for the single-pulse model, which is then extended to describe the pulse-train model in the case of evenly timed, uniform pulses. This renewal-process description provides an accurate and computationally efficient model of electrical stimulation of single auditory nerve fibers by a cochlear implant that may be extended to other forms of electrical neural stimulation."
Model Type: Connectionist Network
Cell Type(s): Auditory nerve
Model Concept(s): Simplified Models; Audition
Simulation Environment: MATLAB (web link to model)
References:
Bruce IC, Irlicht LS, White MW, O'Leary SJ, Clark GM. (2000). Renewal-process approximation of a stochastic threshold model for electrical neural stimulation. Journal of computational neuroscience. 9 [PubMed]
Bruce IC, White MW, Irlicht LS, O'Leary SJ, Clark GM. (1999). The effects of stochastic neural activity in a model predicting intensity perception with cochlear implants: low-rate stimulation. IEEE transactions on bio-medical engineering. 46 [PubMed]
Bruce IC et al. (1999). A stochastic model of the electrically stimulated auditory nerve: pulse-train response. IEEE transactions on bio-medical engineering. 46 [PubMed]
Bruce IC et al. (1999). A stochastic model of the electrically stimulated auditory nerve: single-pulse response. IEEE transactions on bio-medical engineering. 46 [PubMed]