ModelDB: Models that contain CalC Calcium Calculator

Simulation Environment: CalC Calcium Calculator

Determinants of fast calcium dynamics in dendritic spines and dendrites (Cornelisse et al. 2007)

http://web.njit.edu/~matveev/calc.html
CalC ("Calcium Calculator") is a modeling tool for integrating the 3D reaction-diffusion problem (or the corresponding reduced 1D and 2D problems) arising in biophysical modeling of intracellular calcium dynamics. CalC simulates the entry of calcium into a volume through point-like channels, and its diffusion, buffering and binding to calcium receptors.

Top authors for CalC Calcium Calculator:

Cornelisse LN (1)
van Elburg RA (1)
Meredith RM (1)
Yuste R (1)
Mansvelder HD (1)

Top concepts studied with CalC Calcium Calculator:

Calcium dynamics (1)

Top neurons studied with CalC Calcium Calculator:

Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell (1)

Top references cited by these models:

Allbritton NL, Meyer T, Stryer L. (1992). Range of messenger action of calcium ion and inositol 1,4,5-trisphosphate. Science (New York, N.Y.). 258 (1)
Stuart GJ, Sakmann B. (1994). Active propagation of somatic action potentials into neocortical pyramidal cell dendrites. Nature. 367 (1)
Koester HJ, Sakmann B. (1998). Calcium dynamics in single spines during coincident pre- and postsynaptic activity depend on relative timing of back-propagating action potentials and subthreshold excitatory postsynaptic potentials. Proceedings of the National Academy of Sciences of the United States of America. 95 (1)
Kits KS, de Vlieger TA, Kooi BW, Mansvelder HD. (1999). Diffusion barriers limit the effect of mobile calcium buffers on exocytosis of large dense cored vesicles. Biophysical journal. 76 (1)
Lee SH, Schwaller B, Neher E. (2000). Kinetics of Ca2+ binding to parvalbumin in bovine chromaffin cells: implications for [Ca2+] transients of neuronal dendrites. The Journal of physiology. 525 Pt 2 (1)