NEURON mod files from the paper: Cassarà AM, Hagberg GE, Bianciardi M, Migliore M, Maraviglia B. Realistic simulations of neuronal activity: A contribution to the debate on direct detection of neuronal currents by MRI. Neuroimage. 39:87-106 (2008). In this paper, we use a detailed calculation of the magnetic field produced by the neuronal currents propagating over a hippocampal CA1 pyramidal neuron placed inside a cubic MR voxel of length 1.2 mm to estimate the Magnetic Resonance signal.
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Hippocampus CA1 pyramidal GLU cell
Currents: I Na,t; I A; I K; I h
Receptors: AMPA
Transmitters: Glutamate
Model Concept(s): Active Dendrites; Detailed Neuronal Models; Extracellular Fields
Simulation Environment: NEURON
References:
Cassarà AM, Hagberg GE, Bianciardi M, Migliore M, Maraviglia B. (2008). Realistic simulations of neuronal activity: a contribution to the debate on direct detection of neuronal currents by MRI. NeuroImage. 39 [PubMed]
Cassarà AM, Maraviglia B. (2008). Microscopic investigation of the resonant mechanism for the implementation of nc-MRI at ultra-low field MRI. NeuroImage. 41 [PubMed]