Cerebellar Golgi cell (Solinas et al. 2007a, 2007b)

"... Our results suggest that a complex complement of ionic mechanisms is needed to fine-tune separate aspects of the neuronal response dynamics. Simulations also suggest that the Golgi cell may exploit these mechanisms to obtain a fine regulation of timing of incoming mossy fiber responses and granular layer circuit oscillation and bursting."

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Cerebellum

Cell Type(s): Cerebellum golgi cell

Currents: I Na,p; I Na,t; I T low threshold; I A; I K; I M; I K,Ca; I Sodium; I Calcium; I Potassium; I h

Genes: HCN1

Model Concept(s): Activity Patterns; Oscillations

Simulation Environment: NEURON; neuroConstruct (web link to model)

Implementer(s): D'Angelo, Egidio [dangelo at unipv.it]; De Schutter, Erik [erik at oist.jp]


Solinas S et al. (2007). Computational reconstruction of pacemaking and intrinsic electroresponsiveness in cerebellar Golgi cells. Frontiers in cellular neuroscience 1 [PubMed]

Solinas S et al. (2007). Fast-reset of pacemaking and theta-frequency resonance patterns in cerebellar golgi cells: simulations of their impact in vivo. Frontiers in cellular neuroscience 1 [PubMed]