Spike frequency adaptation in the LGMD (Peron and Gabbiani 2009)

This model is used in the referenced paper to demonstrate that a model of an SK-like calcium-sensitive potassium (KCa) conductance can replicate the spike frequency adaptation (SFA) of the locust lobula giant movement detector (LGMD) neuron. The model simulates current injection experiments with and without KCa block in the LGMD, as well as visual stimulation experiments with and without KCa block.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Locust Lobula Giant Movement Detector (LGMD) neuron

Currents: I Na,t; I K,Ca; I Calcium; I Krp

Receptors: GabaA; Cholinergic Receptors

Model Concept(s): Spike Frequency Adaptation; Vision

Simulation Environment: MATLAB

Implementer(s): Gabbiani, F; Peron, Simon [perons at janelia.hhmi.org]

References:

Peron S, Gabbiani F. (2009). Spike frequency adaptation mediates looming stimulus selectivity in a collision-detecting neuron. Nature neuroscience. 12 [PubMed]