" ... We present here a new method that allows extracting estimates of the full time course of excitatory and inhibitory conductances from single-trial Vm recordings. This method is based on oversampling of the Vm . We test the method numerically using models of increasing complexity. Finally, the method is evaluated using controlled conductance injection in cortical neurons in vitro using the dynamic-clamp technique. ..."
Model Type: Neuron or other electrically excitable cell
Model Concept(s): Parameter Fitting; Methods
Simulation Environment: MATLAB
Implementer(s): Bedard, Claude [bedard at unic.cnrs-gif.fr]
References:
Bédard C, Béhuret S, Deleuze C, Bal T, Destexhe A. (2012). Oversampling method to extract excitatory and inhibitory conductances from single-trial membrane potential recordings. Journal of neuroscience methods. 210 [PubMed]