Direct recruitment of S1 pyramidal cells and interneurons via ICMS (Overstreet et al., 2013)

Study of the pyramidal cells and interneurons recruited by intracortical microstimulation in primary somatosensory cortex. Code includes morphological models for seven types of pyramidal cells and eight types of interneurons, NEURON code to simulate ICMS, and an artificial reconstruction of a 3D slab of cortex implemented in MATLAB.

Model Type: Axon

Cell Type(s): Neocortex U1 L6 pyramidal corticalthalamic GLU cell; Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell; Neocortex bitufted interneuron

Currents: I Na,p; I_Ks

Model Concept(s): Intracortical Microstimulation

Simulation Environment: NEURON; MATLAB

Implementer(s): Overstreet, Cynthia [cynthiakoverstreet at]


Overstreet CK, Klein JD, Helms Tillery SI. (2013). Computational modeling of direct neuronal recruitment during intracortical microstimulation in somatosensory cortex. Journal of neural engineering 10 [PubMed]