Drosophila 3rd instar larval aCC motoneuron (Gunay et al. 2015)


Single compartmental, ball-and-stick models implemented in XPP and full morphological model in Neuron. Paper has been submitted and correlates anatomical properties with electrophysiological recordings from these hard-to-access neurons. For instance we make predictions about location of the spike initiation zone, channel distributions, and synaptic input parameters.

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Drosophila

Currents: I Na,p; I Na,t; I A; I K

Receptors: Cholinergic Receptors

Simulation Environment: NEURON; XPPAUT; MATLAB

Implementer(s): Gunay, Cengiz [cgunay at emory.edu]; Sieling, Fred [fred.sieling at gmail.com]; Prinz, Astrid [astrid.prinz at emory.edu]

References:

G√ľnay C et al. (2015). Distal spike initiation zone location estimation by morphological simulation of ionic current filtering demonstrated in a novel model of an identified Drosophila motoneuron. PLoS computational biology 11 [PubMed]