Hippocampal Mossy Fiber bouton: presynaptic KV7 channel function (Martinello et al 2019)


Model Type: Synapse

Region(s) or Organism(s): Hippocampus

Currents: I A; I CAN; I K,leak; I M; I Na,t; I K

Receptors: AMPA

Transmitters: Glutamate

Model Concept(s): Action Potentials

Simulation Environment: NEURON

Implementer(s): Migliore, Michele [Michele.Migliore at Yale.edu]; Giacalone, Elisabetta [elisabetta.giacalone at pa.ibf.cnr.it]

References:

Martinello K, Giacalone E, Migliore M, Brown DA, Shah MM. (2019). The subthreshold-active KV7 current regulates neurotransmission by limiting spike-induced Ca2+ influx in hippocampal mossy fiber synaptic terminals. Communications biology. 2 [PubMed]


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