Inspired by experiments showing the generation of place fields in hippocampal CA1 neurons, this model describes CA3 to CA1 synaptic plasticity occurring on behavioral time-scales (order of seconds). Presynaptic activity induces LTP and LTD eligibility traces which are converted into synaptic changes upon the occurrence of an instructive signal, corresponding to the plateau potential in experiments.
Model Type: Synapse
Region(s) or Organism(s): Hippocampus
Model Concept(s): Synaptic Plasticity; Place cell/field; Eligibility traces
Simulation Environment: MATLAB
References:
Cone I, Shouval HZ. (2021). Behavioral time scale plasticity of place fields: Mathematical analysis Front. Comput. Neurosci.