An agent-based computational model for cortical layer formation (Bauer et al 2021)

This computational model can account for layer-specific neuron numbers in various different cortical structures. It is agent-based and is initiated from a small homogeneous pool of precursor cells. The file includes the main function that induces the activation of multiple "modules" within a gene regulatory network.

Model Type: Agent-based model

Region(s) or Organism(s): Neocortex

Model Concept(s): Development

Simulation Environment: Cx3Dp


Bauer R, Clowry GJ, Kaiser M. (2021). Creative destruction: a basic computational model of cortical layer formation Cerebral cortex (New York, N.Y. : 1991) 31 [PubMed]