This model describes the basis of pulsatile insulin secretion from islet beta-cells at basal levels of glucose, where the cells are not electrically active.
Currents: ATP-senstive potassium current
Simulation Environment: XPPAUT
Implementer(s): Bertram, Richard [rbertram at fsu.edu]
References:
Fletcher PA, Marinelli I, Bertram R, Satin LS, Sherman AS. (2022). Pulsatile Basal Insulin Secretion is Driven by Glycolytic Oscillations Physiology (Bethesda, Md.). 37 [PubMed]