Human and mouse Purkinje cell models (Masoli et al., 2024)


New Purkinje cell models based on Masoli et al. 2015 and 2017. The main differences are: mouse and human morphologies. Revised ionic channels distribution

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Cerebellum

Cell Type(s): Cerebellum Purkinje GABA cell

Currents:

Receptors:

Genes:

Transmitters:

Model Concept(s):

Simulation Environment: NEURON

Implementer(s): Masoli, Stefano [stefano.masoli at unipv.it]

References:

Masoli S et al. (2024). Human Purkinje cells outperform mouse Purkinje cells in dendritic complexity and computational capacity. Communications biology. 7 [PubMed]


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