" ... we show that the canonical circuit (Douglas et al. 1989, Douglas and Martin 1991) can, with a few modifications, model the primate FEF. The spike-based network of integrate-and-fire neurons was tested in tasks that were used in electrophysiological experiments in behaving macaque monkeys. The dynamics of the model matched those of neurons observed in the FEF, and the behavioral results matched those observed in psychophysical experiments. The close relationship between the model and the cortical architecture allows a detailed comparison of the simulation results with physiological data and predicts details of the anatomical circuit of the FEF."
Model Type: Realistic Network
Region(s) or Organism(s): Neocortex
Simulation Environment: MATLAB
Heinzle J, Hepp K, Martin KA. (2007). A microcircuit model of the frontal eye fields. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]