Spike trains in Hodgkin–Huxley model and ISIs of acupuncture manipulations (Wang et al. 2008)

The Hodgkin-Huxley equations (HH) are parameterized by a number of parameters and shows a variety of qualitatively different behaviors depending on the parameter values. Under stimulation of an external periodic voltage, the ISIs (interspike intervals) of a HH model are investigated in this work, while the frequency of the voltage is taken as the controlling parameter. As well-known, the science of acupuncture and moxibustion is an important component of Traditional Chinese Medicine with a long history. Although there are a number of different acupuncture manipulations, the method for distinguishing them is rarely investigated. With the idea of ISI, we study the electrical signal time series at the spinal dorsal horn produced by three different acupuncture manipulations in Zusanli point and present an effective way to distinguish them.

Model Type: Axon

Cell Type(s): Squid axon

Currents: I Sodium; I Potassium

Model Concept(s): Bursting; Oscillations; Simplified Models; Axonal Action Potentials; Action Potentials; Complementary and alternative medicine

Simulation Environment: XPPAUT

Implementer(s): Wu, Sheng-Nan [snwu at mail.ncku.edu.tw]; Wu, Yung-Hun


Wang J, Si W, Che Y, Fei x. (2008). Spike trains in Hodgkin–Huxley model and of acupuncture manipulations Chaos, Solitons and Fractals. 36

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