Neural model of frog ventilatory rhythmogenesis (Horcholle-Bossavit and Quenet 2009)


"In the adult frog respiratory system, periods of rhythmic movements of the buccal floor are interspersed by lung ventilation episodes. The ventilatory activity results from the interaction of two hypothesized oscillators in the brainstem. Here, we model these oscillators with two coupled neural networks, whose co-activation results in the emergence of new dynamics. .. The biological interest of this formal model is illustrated by the persistence of the relevant dynamical features when perturbations are introduced in the model, i.e. dynamic noises and architecture modifications. The implementation of the networks with clock-driven continuous time neurones provides simulations with physiological time scales."

Model Type: Realistic Network

Model Concept(s): Temporal Pattern Generation; Oscillations; Synchronization

Simulation Environment: MATLAB

References:

Horcholle-Bossavit G, Quenet B. (2009). Neural model of frog ventilatory rhythmogenesis. Bio Systems. 97 [PubMed]


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