A simplified cerebellar Purkinje neuron (the PPR model) (Brown et al. 2011)


These models were implemented in NEURON by Sherry-Ann Brown in the laboratory of Leslie M. Loew. The files reproduce Figures 2c-f from Brown et al, 2011 "Virtual NEURON: a Strategy For Merged Biochemical and Electrophysiological Modeling".

Model Type: Neuron or other electrically excitable cell; Dendrite

Region(s) or Organism(s): Cerebellum

Cell Type(s): Cerebellum Purkinje GABA cell

Currents: I Na,p; I p,q; I A; I K; I M; I K,Ca; I Sodium; I Calcium; I Potassium

Model Concept(s): Dendritic Action Potentials; Simplified Models; Active Dendrites; Influence of Dendritic Geometry; Detailed Neuronal Models; Intrinsic plasticity; Methods; Synaptic Integration

Simulation Environment: NEURON

Implementer(s): Brown, Sherry-Ann [sabrown at student.uchc.edu]

References:

Brown SA, Moraru II, Schaff JC, Loew LM. (2011). Virtual NEURON: a strategy for merged biochemical and electrophysiological modeling. Journal of computational neuroscience. 31 [PubMed]


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