In this paper, we studied what features of realistic full model activity patterns can and cannot be preserved by morphologically reduced models. To this end, we reduced the morphological complexity of a full globus pallidus neuron model possessing active dendrites and compared its spontaneous and driven responses to those of the reduced models.
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Globus pallidus neuron
Simulation Environment: GENESIS
Implementer(s): Hendrickson, Eric B [eric.b.hendrickson at gmail.com]
Hendrickson EB, Edgerton JR, Jaeger D. (2011). The capabilities and limitations of conductance-based compartmental neuron models with reduced branched or unbranched morphologies and active dendrites. Journal of computational neuroscience. 30 [PubMed]