This model examined how distal oscillatory inhibition influences the firing of a biophysically-detailed layer 5 pyramidal neuron model.
Model Type: Neuron or other electrically excitable cell
Region(s) or Organism(s): Neocortex
Cell Type(s): Neocortex L5/6 pyramidal GLU cell
Currents: I K,Ca; I Na, leak
Receptors: AMPA
Transmitters: Dopamine
Model Concept(s): Intrinsic plasticity
Simulation Environment: NEURON; MATLAB
Implementer(s): Moradi, Keivan [k.moradi at gmail.com]; Robinson, H.P.C. [hpcr at cam.ac.uk]; Small, Michael ; Li, Xiumin
References:
Li X, Morita K, Robinson HP, Small M. (2013). Control of layer 5 pyramidal cell spiking by oscillatory inhibition in the distal apical dendrites: a computational modeling study. Journal of neurophysiology. 109 [PubMed]