Mixed mode oscillations as a mechanism for pseudo-plateau bursting (Vo et al. 2010)


"We combine bifurcation analysis with the theory of canard-induced mixed mode oscillations to investigate the dynamics of a novel form of bursting. This bursting oscillation, which arises from a model of the electrical activity of a pituitary cell, is characterized by small impulses or spikes riding on top of an elevated voltage plateau. ..."

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Pituitary cell

Currents: I A; I K; I Calcium

Model Concept(s): Bursting; Oscillations; Bifurcation

Simulation Environment: XPP (web link to model)

References:

Vo T, Bertram R, Tabak J, Wechselberger M. (2010). Mixed mode oscillations as a mechanism for pseudo-plateau bursting. Journal of computational neuroscience. 28 [PubMed]


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