Neural-field model of generalized seizures (Zhao et al., 2015)

The mechanisms underlying generalized seizures are explored with neural field theory. A corticothalamic neural field model is used to explore changes leading to pathological seizure states. It is found that absence seizures arise from instabilities in the system and replicate experimental studies in numerous animal models and clinical studies.

Model Type: Neural mass

Model Concept(s): Epilepsy

Simulation Environment: MATLAB


Zhao X, Robinson PA. (2015). Generalized seizures in a neural field model with bursting dynamics. Journal of computational neuroscience. 39 [PubMed]

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