Quantitative assessment of computational models for retinotopic map formation (Hjorth et al. 2015)

"Molecular and activity-based cues acting together are thought to guide retinal axons to their terminal sites in vertebrate optic tectum or superior colliculus (SC) to form an ordered map of connections. The details of mechanisms involved, and the degree to which they might interact, are still not well understood. We have developed a framework within which existing computational models can be assessed in an unbiased and quantitative manner against a set of experimental data curated from the mouse retinocollicular system. ..."

Model Type: Realistic Network

Region(s) or Organism(s): Superior colliculus

Model Concept(s): Methods; Development

Simulation Environment: MATLAB (web link to model); C or C++ program (web link to model); R (web link to model)

Implementer(s): Hjorth, Johannes [hjorth at csc.kth.se]


Hjorth JJ, Sterratt DC, Cutts CS, Willshaw DJ, Eglen SJ. (2015). Quantitative assessment of computational models for retinotopic map formation. Developmental neurobiology. 75 [PubMed]

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