A stereotypical pyramidal neuron morphology with ion channel parameter combinations that reproduce firing patterns of one young and one aged rhesus monkey L3 PFC pyramidal neurons. Parameters were found through an automated optimization method.
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Neocortex L2/3 pyramidal GLU cell
Simulation Environment: NEURON
Rumbell TH et al. (2016). Automated evolutionary optimization of ion channel conductances and kinetics in models of young and aged rhesus monkey pyramidal neurons. Journal of computational neuroscience. 41 [PubMed]