" ... Here we present a biophysical model of a DA VTA neuron based on 3D morphological reconstruction and electrophysiological data, showing how opiates withdrawal-driven morphological and electrophysiological changes could affect the firing rate and discharge pattern...."
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Ventral tegmental area dopamine neuron
Model Concept(s): Activity Patterns; Addiction
Simulation Environment: NEURON
Implementer(s): Enrico, Paolo [enrico at uniss.it]
References:
Enrico P et al. (2016). Morphofunctional alterations in ventral tegmental area dopamine neurons in acute and prolonged opiates withdrawal. A computational perspective. Neuroscience. 322 [PubMed]