CA1 pyramidal cells, basket cells, ripples (Malerba et al 2016)

Model of CA1 pyramidal layer Ripple activity, triggered when receiving current input (to represent CA3 sharp-waves). Cells are Adaptive-Exponential Integrate and Fire neurons, receiving independent OU noise.

Model Type: Realistic Network

Cell Type(s): Hippocampus CA1 pyramidal GLU cell; Hippocampus CA1 PV+ fast-firing interneuron

Receptors: GabaA; AMPA

Model Concept(s): Oscillations; Sleep; Brain Rhythms

Simulation Environment: MATLAB

References:

Malerba P, Krishnan GP, Fellous JM, Bazhenov M. (2016). Hippocampal CA1 Ripples as Inhibitory Transients. PLoS computational biology. 12 [PubMed]