The model shows how the experimentally observed increase in the dendritic density of Ih and IA could have a major role in constraining the temporal integration window for the main CA1 synaptic inputs.
Model Type: Dendrite
Cell Type(s): Hippocampus CA1 pyramidal GLU cell
Currents: I Na,t; I A; I K; I h
Receptors: AMPA
Transmitters: Glutamate
Model Concept(s): Action Potential Initiation; Coincidence Detection; Active Dendrites; Detailed Neuronal Models
Simulation Environment: NEURON
Implementer(s): Migliore, Michele [Michele.Migliore at Yale.edu]
References:
Migliore M. (2003). On the integration of subthreshold inputs from Perforant Path and Schaffer Collaterals in hippocampal CA1 pyramidal neurons. Journal of computational neuroscience. 14 [PubMed]