A model of rodent mechanoreceptors (LTMRs) (Medlock et al., 2024)


"... unlike the dichotomous frequency preference characteristic of RA1 and RA2/Pacinian afferents in other species, rodent RAs fell along a continuum. Fitting generalized linear models (GLMs) to experimental data reproduced the reliability and precision of rodent RAs. The resulting model parameters highlight key mechanistic differences across the RA spectrum; specifically, the integration window of different RAs transitions from wide to narrow as tuning preferences across the population move from low to high frequencies..."

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s):

Cell Type(s):

Currents:

Receptors:

Genes:

Transmitters:

Model Concept(s): Touch

Simulation Environment: MATLAB

Implementer(s): Medlock, Laura [laura.medlock at mail.utoronto.ca]

References:

Medlock L et al. (2024). Encoding of vibrotactile stimuli by mechanoreceptors in rodent glabrous skin. The Journal of neuroscience : the official journal of the Society for Neuroscience. [PubMed]


This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.