Pyramidal cells, stellate cells and fast-spiking interneurons receive running speed dependent glutamatergic input from septo-entorhinal projections. These models simulate the integration of this input by the different MEC celltypes.
Model Type: Neuron or other electrically excitable cell
Region(s) or Organism(s): Entorhinal cortex
Cell Type(s): Entorhinal cortex pyramidal cell; Entorhinal cortex stellate cell; Entorhinal cortex fast-spiking interneuron
Receptors: AMPA
Transmitters: Glutamate
Model Concept(s): Synaptic Integration; Simplified Models
Simulation Environment: NEURON
Implementer(s): Justus, Daniel [daniel.justus at dzne.de]
References:
Justus D et al. (2017). Glutamatergic synaptic integration of locomotion speed via septoentorhinal projections. Nature neuroscience. 20 [PubMed]