Menon et al. (2013) describes the experimentally-observed variation in synaptic AMPA and NMDA conductance as a function of distance from the soma. This model explores the effect of this variation on somatic EPSPs and dendritic spike initiation, as compared to the case of uniform AMPA and NMDA conductance.
Region(s) or Organism(s): Hippocampus
Cell Type(s): Hippocampus CA1 pyramidal GLU cell
Model Concept(s): Synaptic Integration
Simulation Environment: NEURON
Implementer(s): Menon, Vilas [vilasmenon2008 at u dot northwestern dot edu]