Reproducibility and comparability of models for astrocyte Ca2+ excitability (Manninen et al 2017)

We tested the reproducibility and comparability of four astrocyte models (Manninen, Havela, Linne, 2017). We implemented and ran the python models using Jupyter Notebook. Model code produces results of Figure 1 and Figures 3-5 and partly Figure 2 in Manninen, Havela, Linne (2017).

Model Type: Glia

Region(s) or Organism(s): Generic

Cell Type(s): Astrocyte

Receptors: mGluR5; IP3

Transmitters: Glutamate

Model Concept(s): Oscillations; Signaling pathways; Calcium dynamics

Simulation Environment: Python (web link to model)

Implementer(s): Manninen, Tiina [tiina.h.manninen at gmail.com]

References:

Manninen T, Havela R, Linne M-L. (2017). Reproducibility and comparability of computational models for astrocyte calcium excitability Front. Neuroinform..