The cannula artifact (Chandler & Hodgkin 1965)

Chandler and Hodgkin 1965 describes how using a high impedance electrode can lead to squid axon recordings that appear to overshoot the sodium reversal potential, thus resolving controversial recordings at the time.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Squid axon

Model Concept(s): Methods; Action Potentials; Tutorial/Teaching

Simulation Environment: NEURON

Implementer(s): Hines, Michael [Michael.Hines at]


Chandler WK, Hodgkin AL. (1965). The effect of internal sodium on the action potential in the presence of different internal anions. The Journal of physiology. 181 [PubMed]

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