The neuro-electronic junction (planar and engulfed electrodes) (Massobrio et al 2018)

Models of the neuron, planar (GPµE) and mushroom-shaped (GMµE) microelectrodes, neuro-electronic junction (microelectrode-electrolyte interface, cleft effect, and protein-glycocalyx electric double layer) are presented. Then, neuronal electrical activity is simulated by HSPICE software, and analyzed as a function of the most sensitive biophysical models parameters such as the neuron-microelectrode cleft width, spreading and seal resistances, ion-channel densities, double-layer properties, and microelectrode geometries.

Model Type: Extracellular

Cell Type(s): Hodgkin-Huxley neuron

Model Concept(s): Methods

Simulation Environment: HSPICE; ngspice


Massobrio G, Martinoia S, Massobrio P. (2018). Equivalent Circuit of the Neuro-Electronic Junction for Signal Recordings From Planar and Engulfed Micro-Nano-Electrodes. IEEE transactions on biomedical circuits and systems. 12 [PubMed]

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