2D model of olfactory bulb gamma oscillations (Li and Cleland 2017)

This is a biophysical model of the olfactory bulb (OB) that contains three types of neurons: mitral cells, granule cells and periglomerular cells. The model is used to study the cellular and synaptic mechanisms of OB gamma oscillations. We concluded that OB gamma oscillations can be best modeled by the coupled oscillator architecture termed pyramidal resonance inhibition network gamma (PRING).

Model Type: Realistic Network

Cell Type(s): Olfactory bulb main mitral GLU cell; Olfactory bulb main interneuron granule MC GABA cell; Olfactory bulb main interneuron periglomerular GABA cell

Receptors: AMPA; NMDA; GabaA

Model Concept(s): Olfaction

Simulation Environment: NEURON

Implementer(s): Li, Guoshi [guoshi_li at med.unc.edu]

References:

Li G, Cleland TA. (2017). A coupled-oscillator model of olfactory bulb gamma oscillations. PLoS computational biology. 13 [PubMed]