Generating neuron geometries for detailed 3D simulations using AnaMorph (Morschel et al 2017)


"Generating realistic and complex computational domains for numerical simulations is often a challenging task. In neuroscientific research, more and more one-dimensional morphology data is becoming publicly available through databases. This data, however, only contains point and diameter information not suitable for detailed three-dimensional simulations. In this paper, we present a novel framework, AnaMorph, that automatically generates water-tight surface meshes from one-dimensional point-diameter files. These surface triangulations can be used to simulate the electrical and biochemical behavior of the underlying cell. ..."

Model Type: Neuron or other electrically excitable cell

Model Concept(s): Methods

Simulation Environment: C or C++ program (web link to model)

Implementer(s): Morschel, Konstantin

References:

Mörschel K, Breit M, Queisser G. (2017). Generating Neuron Geometries for Detailed Three-Dimensional Simulations Using AnaMorph. Neuroinformatics. 15 [PubMed]


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