Factors contribution to GDP-induced [Cl-]i transients (Lombardi et al 2019)

This models are used to evaluate which factors influence the GDP (giant depolarizing potential) induced [Cl-]I transients based on a initial model of P. Jedlicka

Model Type: Neuron or other electrically excitable cell; Dendrite; Synapse

Region(s) or Organism(s): Mouse; Hippocampus

Cell Type(s): Hippocampus CA3 pyramidal GLU cell

Receptors: GabaA

Transmitters: Gaba

Model Concept(s): Synaptic Plasticity

Simulation Environment: NEURON


Lombardi A, Jedlicka P, Luhmann HJ, Kilb W. (2019). Interactions Between Membrane Resistance, GABA-A Receptor Properties, Bicarbonate Dynamics and Cl-Transport Shape Activity-Dependent Changes of Intracellular Cl- Concentration International journal of molecular sciences. 20 [PubMed]

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