MultiScale Optimized Neuronal Intramembrane Cavitation (SONIC) model (Lemaire et al. 2019)


Jupyter Notebooks to reproduce data and figures of the SONIC paper (Lemaire et al. 2019) describing a computationally efficient variant to simulate ultrasound neuromodulation by intramembrane cavitation in cortical neurons.

Cell Type(s): Subthalamic nucleus principal GABA cell; Neocortex spiking regular (RS) neuron; Neocortex fast spiking (FS) interneuron; Neocortex spiking low threshold (LTS) neuron

Model Concept(s): Action Potentials

Simulation Environment: Python; NEURON

References:

Lemaire T, Neufeld E, Kuster N, Micera S. (2019). Understanding ultrasound neuromodulation using a computationally efficient and interpretable model of intramembrane cavitation. Journal of neural engineering. 16 [PubMed]


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