Layer-specific pyramidal cell props underlie diverse ACC motor + limbic networks (Medalla et al '21)

"A MATLAB-based model of pyramidal-interneuron network was extended from []... to simulate how intrinsic biophysical properties and inhibition can affect network synchrony and oscillatory frequencies in ACC L3 and L5... Four different networks were simulated depending on a subset of empirically derived biophysical, morphological and connectional properties of lamina- and target- specific ACC pyramidal neurons... our model is constrained by in vitro whole cell patch clamp recording data from the soma."

Cell Type(s): Hodgkin-Huxley neuron; Abstract Wang-Buzsaki neuron

Model Concept(s): Oscillations; Action Potentials; Spike Frequency Adaptation

Simulation Environment: MATLAB


Chang W et al. (2021). Layer-specific pyramidal neuron properties underlie diverse anterior cingulate cortical motor and limbic networks Cerebral Cortex.

This website requires cookies and limited processing of your personal data in order to function. By continuing to browse or otherwise use this site, you are agreeing to this use. See our Privacy policy and how to cite and terms of use.