Model for pusatile insulin secretion at basal levels of glucose (Fletcher et al, 2022)


This model describes the basis of pulsatile insulin secretion from islet beta-cells at basal levels of glucose, where the cells are not electrically active.

Currents: ATP-senstive potassium current

Simulation Environment: XPPAUT

Implementer(s): Bertram, Richard [rbertram at fsu.edu]

References:

Fletcher PA, Marinelli I, Bertram R, Satin LS, Sherman AS. (2022). Pulsatile Basal Insulin Secretion is Driven by Glycolytic Oscillations Physiology (Bethesda, Md.). 37 [PubMed]


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