The present modeling study suggests that persistent, low-threshold, rapidly activating sodium currents have a key role in breakdown of accommodation, and that breakdown of accommodation can be used as a tool for studying persistent sodium current under normal and pathological conditions. See paper for more and details.
Model Type: Neuron or other electrically excitable cell
Simulation Environment: MATLAB
Implementer(s): Hennings, Kristian [krist at hst.auc.dk]
Hennings K, Arendt-Nielsen L, Andersen OK. (2005). Breakdown of accommodation in nerve: a possible role for persistent sodium current. Theoretical biology & medical modelling. 2 [PubMed]