Continuum model of tubulin-driven neurite elongation (Graham et al 2006)

This model investigates the elongation over time of a single developing neurite (axon or dendrite). Our neurite growth model describes the elongation of a single,unbranched neurite in terms of the rate of extension of the microtubule cytoskeleton. The cytoskeleton is not explicitly modelled, but its construction is assumed to depend on the available free tubulin at the growing neurite tip.

Model Type: Axon; Dendrite

Model Concept(s): Development; Olfaction

Simulation Environment: MATLAB

Implementer(s): Graham, Bruce [B.Graham at]


Graham BP, Lauchlan K, Mclean DR. (2006). Dynamics of outgrowth in a continuum model of neurite elongation. Journal of computational neuroscience. 20 [PubMed]

Graham BP, van Ooyen A. (2006). Mathematical modelling and numerical simulation of the morphological development of neurons. BMC neuroscience. 7 Suppl 1 [PubMed]

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