Markovian model for single-channel recordings of Ik_1 in ventricular cells (Matsuoka et al 2003)


The interaction between many currents in a cardiac ventricular model are examined in this paper. One of the main contributions come from a current called IK_1. An XPP version of this model was supplied by Hsieng-Jung Lai, Jiun-Shian Wu, Sheng-Nan Wu, Ruey J. Sung, Han-Dong Chang. Please see paper and model for more and details.

Model Type: Channel/Receptor

Currents: I K

Model Concept(s): Ion Channel Kinetics; Heart disease; Cardiac pacemaking; Markov-type model

Simulation Environment: XPPAUT

Implementer(s): Wu, Sheng-Nan [snwu at mail.ncku.edu.tw]; Chang, Han-Dong; Wu, Jiun-Shian [coolneon at gmail.com]; Sung, Ruey J ; Lai, Hsing-Jung

References:

Matsuoka S, Sarai N, Kuratomi S, Ono K, Noma A. (2003). Role of individual ionic current systems in ventricular cells hypothesized by a model study. The Japanese journal of physiology. 53 [PubMed]


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