Reciprocal regulation of rod and cone synapse by NO (Kourennyi et al 2004)

We constructed models of rod and cone photoreceptors using NEURON software to predict how changes in Ca channels would affect the light response in these cells and in postsynaptic horizontal cells.

Model Type: Neuron or other electrically excitable cell

Cell Type(s): Retina photoreceptor cone GLU cell

Currents: I Chloride; I K; I h; I K,Ca; I Calcium; I Potassium

Transmitters: NO

Model Concept(s): Calcium dynamics; Vision

Simulation Environment: NEURON

Implementer(s): Kourennyi, Dmitri E [dek at case.edu]; Liu, Xiaodong [xliu22 at jhmi.edu]

References:

Kourennyi DE et al. (2004). Reciprocal modulation of calcium dynamics at rod and cone photoreceptor synapses by nitric oxide. Journal of neurophysiology. 92 [PubMed]