Vesicular pool simulations of synaptic depression (Aristizabal and Glavinovic 2004)

"Synaptic release was simulated using a Simulink sequential storage model with three vesicular pools. Modeling was modular and easily extendable to the systems with greater number of vesicular pools, parallel input, or time-varying parameters. ... Finally, the method was tested experimentally using the rat phrenic-diaphragm neuromuscular junction." See paper for more and details.

Model Type: Synapse

Simulation Environment: MATLAB; Simulink


Aristizabal F, Glavinovic MI. (2004). Simulation and parameter estimation of dynamics of synaptic depression. Biological cybernetics. 90 [PubMed]

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