This classic model of ventricular myocardial fibres was implemented by Francois Gannier. "... Four individual components of ionic current were formulated mathematically in terms of Hodgkin-Huxley type equations. The model incorporates two voltage- and time-dependent inward currents, the excitatory inward sodium current, illa, and a secondary or slow inward current, is, primarily carried by calcium ions. A time-independent outward potassium current, iK1, exhibiting inward-going rectification, and a voltage- and time-dependent outward current, i.1, primarily carried by potassium ions, are further elements of the model...."
Model Type: Neuron or other electrically excitable cell
Cell Type(s): Cardiac ventricular cell
Currents: I K; I Sodium; I Calcium; I Potassium
Model Concept(s): Ion Channel Kinetics; Action Potentials
Simulation Environment: NEURON
Implementer(s): Gannier, Francois [francois.gannier at univ-tours.fr]
References:
Beeler GW, Reuter H. (1977). Reconstruction of the action potential of ventricular myocardial fibres. The Journal of physiology. 268 [PubMed]