Allbritton NL, Meyer T, Stryer L. (1992). Range of messenger action of calcium ion and inositol 1,4,5-trisphosphate. Science (New York, N.Y.). 258 [PubMed]

Ando H et al. (2006). IRBIT suppresses IP3 receptor activity by competing with IP3 for the common binding site on the IP3 receptor. Molecular cell. 22 [PubMed]

Ando H, Mizutani A, Matsu-ura T, Mikoshiba K. (2003). IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor. The Journal of biological chemistry. 278 [PubMed]

Aravind P et al. (2008). Regulatory and structural EF-hand motifs of neuronal calcium sensor-1: Mg 2+ modulates Ca 2+ binding, Ca 2+ -induced conformational changes, and equilibrium unfolding transitions. Journal of molecular biology. 376 [PubMed]

Barylko B et al. (2009). Palmitoylation controls the catalytic activity and subcellular distribution of phosphatidylinositol 4-kinase II{alpha}. The Journal of biological chemistry. 284 [PubMed]

Beech DJ, Bernheim L, Mathie A, Hille B. (1991). Intracellular Ca2+ buffers disrupt muscarinic suppression of Ca2+ current and M current in rat sympathetic neurons. Proceedings of the National Academy of Sciences of the United States of America. 88 [PubMed]

Berridge MJ. (2009). Inositol trisphosphate and calcium signalling mechanisms. Biochimica et biophysica acta. 1793 [PubMed]

Berridge MJ, Irvine RF. (1984). Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature. 312 [PubMed]

Bezprozvanny I, Watras J, Ehrlich BE. (1991). Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum. Nature. 351 [PubMed]

Brown DA, Adams PR. (1980). Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone. Nature. 283 [PubMed]

Brown DA, Hughes SA, Marsh SJ, Tinker A. (2007). Regulation of M(Kv7.2/7.3) channels in neurons by PIP(2) and products of PIP(2) hydrolysis: significance for receptor-mediated inhibition. The Journal of physiology. 582 [PubMed]

Brown DA, Passmore GM. (2009). Neural KCNQ (Kv7) channels. British journal of pharmacology. 156 [PubMed]

Cantley LC. (2002). The phosphoinositide 3-kinase pathway. Science (New York, N.Y.). 296 [PubMed]

Chang CL et al. (2013). Feedback regulation of receptor-induced Ca2+ signaling mediated by E-Syt1 and Nir2 at endoplasmic reticulum-plasma membrane junctions. Cell reports. 5 [PubMed]

Chang CL, Liou J. (2015). Phosphatidylinositol 4,5-Bisphosphate Homeostasis Regulated by Nir2 and Nir3 Proteins at Endoplasmic Reticulum-Plasma Membrane Junctions. The Journal of biological chemistry. 290 [PubMed]

Charpentier F, Mérot J, Loussouarn G, Baró I. (2010). Delayed rectifier K(+) currents and cardiac repolarization. Journal of molecular and cellular cardiology. 48 [PubMed]

Cho H et al. (2002). Acetylcholine-induced phosphatidylinositol 4,5-bisphosphate depletion does not cause short-term desensitization of G protein-gated inwardly rectifying K+ current in mouse atrial myocytes. The Journal of biological chemistry. 277 [PubMed]

Chung J, Nakatsu F, Baskin JM, De Camilli P. (2015). Plasticity of PI4KIIIa interactions at the plasma membrane. EMBO reports. 16 [PubMed]

Clark J et al. (2011). Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry. Nature methods. 8 [PubMed]

Cremona O, De Camilli P. (2001). Phosphoinositides in membrane traffic at the synapse. Journal of cell science. 114 [PubMed]

Cruzblanca H, Koh DS, Hille B. (1998). Bradykinin inhibits M current via phospholipase C and Ca2+ release from IP3-sensitive Ca2+ stores in rat sympathetic neurons. Proceedings of the National Academy of Sciences of the United States of America. 95 [PubMed]

Delmas P, Wanaverbecq N, Abogadie FC, Mistry M, Brown DA. (2002). Signaling microdomains define the specificity of receptor-mediated InsP(3) pathways in neurons. Neuron. 34 [PubMed]

Di Paolo G, De Camilli P. (2006). Phosphoinositides in cell regulation and membrane dynamics. Nature. 443 [PubMed]

Dickson EJ, Falkenburger BH, Hille B. (2013). Quantitative properties and receptor reserve of the IP(3) and calcium branch of G(q)-coupled receptor signaling. The Journal of general physiology. 141 [PubMed]

Dickson EJ, Jensen JB, Hille B. (2014). Golgi and plasma membrane pools of PI(4)P contribute to plasma membrane PI(4,5)P2 and maintenance of KCNQ2/3 ion channel current. Proceedings of the National Academy of Sciences of the United States of America. 111 [PubMed]

Duman JG, Chen L, Hille B. (2008). Calcium transport mechanisms of PC12 cells. The Journal of general physiology. 131 [PubMed]

Falkenburger BH, Dickson EJ, Hille B. (2013). Quantitative properties and receptor reserve of the DAG and PKC branch of G(q)-coupled receptor signaling. The Journal of general physiology. 141 [PubMed]

Falkenburger BH, Jensen JB, Hille B. (2010). Kinetics of M1 muscarinic receptor and G protein signaling to phospholipase C in living cells. The Journal of general physiology. 135 [PubMed]

Falkenburger BH, Jensen JB, Hille B. (2010). Kinetics of PIP2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells. The Journal of general physiology. 135 [PubMed]

Gamper N, Reznikov V, Yamada Y, Yang J, Shapiro MS. (2004). Phosphatidylinositol [correction] 4,5-bisphosphate signals underlie receptor-specific Gq/11-mediated modulation of N-type Ca2+ channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24 [PubMed]

Gamper N, Shapiro MS. (2003). Calmodulin mediates Ca2+-dependent modulation of M-type K+ channels. The Journal of general physiology. 122 [PubMed]

Garner K et al. (2012). Phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) binds and transfers phosphatidic acid. The Journal of biological chemistry. 287 [PubMed]

Gertjegerdes W, Ravens U, Ziegler A. (1979). Time courses of carbachol-induced responses in guinea pig atria under the influence of ouabain, calcium, and rate of stimulation. Journal of cardiovascular pharmacology. 1 [PubMed]

Hammond GR, Machner MP, Balla T. (2014). A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi. The Journal of cell biology. 205 [PubMed]

Hardie RC et al. (2001). Calcium influx via TRP channels is required to maintain PIP2 levels in Drosophila photoreceptors. Neuron. 30 [PubMed]

Hilgemann DW. (2007). On the physiological roles of PIP(2) at cardiac Na+ Ca2+ exchangers and K(ATP) channels: a long journey from membrane biophysics into cell biology. The Journal of physiology. 582 [PubMed]

Hille B, Dickson EJ, Kruse M, Vivas O, Suh BC. (2015). Phosphoinositides regulate ion channels. Biochimica et biophysica acta. 1851 [PubMed]

Hughes S, Marsh SJ, Tinker A, Brown DA. (2007). PIP(2)-dependent inhibition of M-type (Kv7.2/7.3) potassium channels: direct on-line assessment of PIP(2) depletion by Gq-coupled receptors in single living neurons. Pflugers Archiv : European journal of physiology. 455 [PubMed]

Ichikawa H, Terayama R, Yamaai T, Sugimoto T. (2009). Peptide 19 in the rat superior cervical ganglion. Neuroscience. 161 [PubMed]

Itsuki K et al. (2014). PLC-mediated PI(4,5)P2 hydrolysis regulates activation and inactivation of TRPC6/7 channels. The Journal of general physiology. 143 [PubMed]

Jacobowitz D, Woodward JK. (1968). Adrenergic neurons in the cat superior cervical ganglion and cervical sympathetic nerve trunk. A histochemical study. The Journal of pharmacology and experimental therapeutics. 162 [PubMed]

Jensen JB, Lyssand JS, Hague C, Hille B. (2009). Fluorescence changes reveal kinetic steps of muscarinic receptor-mediated modulation of phosphoinositides and Kv7.2/7.3 K+ channels. The Journal of general physiology. 133 [PubMed]

Jentsch TJ. (2000). Neuronal KCNQ potassium channels: physiology and role in disease. Nature reviews. Neuroscience. 1 [PubMed]

Ke XX et al. (2015). Phox2B correlates with MYCN and is a prognostic marker for neuroblastoma development. Oncology letters. 9 [PubMed]

Kim S et al. (2013). The phosphatidylinositol-transfer protein Nir2 binds phosphatidic acid and positively regulates phosphoinositide signalling. EMBO reports. 14 [PubMed]

Kim YJ, Guzman-Hernandez ML, Wisniewski E, Balla T. (2015). Phosphatidylinositol-Phosphatidic Acid Exchange by Nir2 at ER-PM Contact Sites Maintains Phosphoinositide Signaling Competence. Developmental cell. 33 [PubMed]

LIBET B. (1964). SLOW SYNAPTIC RESPONSES AND EXCITATORY CHANGES IN SYMPATHETIC GANGLIA. The Journal of physiology. 174 [PubMed]

Laketa V et al. (2014). PIP3 induces the recycling of receptor tyrosine kinases. Science signaling. 7 [PubMed]

Marrion NV. (1997). Control of M-current. Annual review of physiology. 59 [PubMed]

Martin TF. (2015). PI(4,5)P2-binding effector proteins for vesicle exocytosis. Biochimica et biophysica acta. 1851 [PubMed]

Michell RH. (1975). Inositol phospholipids and cell surface receptor function. Biochimica et biophysica acta. 415 [PubMed]

Micheva KD, Holz RW, Smith SJ. (2001). Regulation of presynaptic phosphatidylinositol 4,5-biphosphate by neuronal activity. The Journal of cell biology. 154 [PubMed]

Murata Y, Okamura Y. (2007). Depolarization activates the phosphoinositide phosphatase Ci-VSP, as detected in Xenopus oocytes coexpressing sensors of PIP2. The Journal of physiology. 583 [PubMed]

Nasuhoglu C et al. (2002). Modulation of cardiac PIP2 by cardioactive hormones and other physiologically relevant interventions. American journal of physiology. Cell physiology. 283 [PubMed]

Paterlini M, Revilla V, Grant AL, Wisden W. (2000). Expression of the neuronal calcium sensor protein family in the rat brain. Neuroscience. 99 [PubMed]

Pawson AJ et al. (2014). The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucleic acids research. 42 [PubMed]

Posor Y, Eichhorn-Grünig M, Haucke V. (2015). Phosphoinositides in endocytosis. Biochimica et biophysica acta. 1851 [PubMed]

Rajebhosale M, Greenwood S, Vidugiriene J, Jeromin A, Hilfiker S. (2003). Phosphatidylinositol 4-OH kinase is a downstream target of neuronal calcium sensor-1 in enhancing exocytosis in neuroendocrine cells. The Journal of biological chemistry. 278 [PubMed]

Rohacs T. (2014). Phosphoinositide regulation of TRP channels. Handbook of experimental pharmacology. 223 [PubMed]

Saarikangas J, Zhao H, Lappalainen P. (2010). Regulation of the actin cytoskeleton-plasma membrane interplay by phosphoinositides. Physiological reviews. 90 [PubMed]

Strahl T, Grafelmann B, Dannenberg J, Thorner J, Pongs O. (2003). Conservation of regulatory function in calcium-binding proteins: human frequenin (neuronal calcium sensor-1) associates productively with yeast phosphatidylinositol 4-kinase isoform, Pik1. The Journal of biological chemistry. 278 [PubMed]

Suh BC, Hille B. (2002). Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis. Neuron. 35 [PubMed]

Szentpetery Z, Várnai P, Balla T. (2010). Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling. Proceedings of the National Academy of Sciences of the United States of America. 107 [PubMed]

Tanimura A et al. (2009). Use of Fluorescence Resonance Energy Transfer-based Biosensors for the Quantitative Analysis of Inositol 1,4,5-Trisphosphate Dynamics in Calcium Oscillations. The Journal of biological chemistry. 284 [PubMed]

Vandenberg JI et al. (2012). hERG K(+) channels: structure, function, and clinical significance. Physiological reviews. 92 [PubMed]

Vivas O, Castro H, Arenas I, Elías-Viñas D, García DE. (2013). PIP2 hydrolysis is responsible for voltage independent inhibition of CaV2.2 channels in sympathetic neurons. Biochemical and biophysical research communications. 432 [PubMed]

Vivas O, Kruse M, Hille B. (2014). Nerve growth factor sensitizes adult sympathetic neurons to the proinflammatory peptide bradykinin. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34 [PubMed]

Wanaverbecq N, Marsh SJ, Al-Qatari M, Brown DA. (2003). The plasma membrane calcium-ATPase as a major mechanism for intracellular calcium regulation in neurones from the rat superior cervical ganglion. The Journal of physiology. 550 [PubMed]

Wang HS et al. (1998). KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel. Science (New York, N.Y.). 282 [PubMed]

Weight FF, Votava J. (1970). Slow synaptic excitation in sympathetic ganglion cells: evidence for synaptic inactivation of potassium conductance. Science (New York, N.Y.). 170 [PubMed]

Willars GB, Nahorski SR, Challiss RA. (1998). Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells. The Journal of biological chemistry. 273 [PubMed]

Winks JS et al. (2005). Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. 25 [PubMed]

Xu C, Watras J, Loew LM. (2003). Kinetic analysis of receptor-activated phosphoinositide turnover. The Journal of cell biology. 161 [PubMed]

Xu JX et al. (2014). Phosphoinositide kinases play key roles in norepinephrine- and angiotensin II-induced increase in phosphatidylinositol 4,5-bisphosphate and modulation of cardiac function. The Journal of biological chemistry. 289 [PubMed]

Yadav S et al. (2015). RDGBa, a PtdIns-PtdOH transfer protein, regulates G-protein-coupled PtdIns(4,5)P2 signalling during Drosophila phototransduction. Journal of cell science. 128 [PubMed]

Zaika O, Tolstykh GP, Jaffe DB, Shapiro MS. (2007). Inositol triphosphate-mediated Ca2+ signals direct purinergic P2Y receptor regulation of neuronal ion channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27 [PubMed]

Zaika O, Zhang J, Shapiro MS. (2011). Combined phosphoinositide and Ca2+ signals mediating receptor specificity toward neuronal Ca2+ channels. The Journal of biological chemistry. 286 [PubMed]

Zhang H et al. (2003). PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents. Neuron. 37 [PubMed]

Zhang H et al. (2013). Membrane microdomain determines the specificity of receptor-mediated modulation of Kv7/M potassium currents. Neuroscience. 254 [PubMed]

Zhao X et al. (2001). Interaction of neuronal calcium sensor-1 (NCS-1) with phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and affects membrane trafficking in COS-7 cells. The Journal of biological chemistry. 276 [PubMed]

Zhou Q et al. (2014). Molecular insights into the membrane-associated phosphatidylinositol 4-kinase IIa. Nature communications. 5 [PubMed]

del Río E, Bevilacqua JA, Marsh SJ, Halley P, Caulfield MP. (1999). Muscarinic M1 receptors activate phosphoinositide turnover and Ca2+ mobilisation in rat sympathetic neurones, but this signalling pathway does not mediate M-current inhibition. The Journal of physiology. 520 Pt 1 [PubMed]