Albert KA et al. (1984). Calcium/phospholipid-dependent protein kinase (protein kinase C) phosphorylates and activates tyrosine hydroxylase. Proceedings of the National Academy of Sciences of the United States of America. 81 [PubMed]

Allen RM. (1977). Dopamine hypersensitivity and tardive dyskinesia. The American journal of psychiatry. 134 [PubMed]

Allgood VE, Powell-Oliver FE, Cidlowski JA. (1990). Vitamin B6 influences glucocorticoid receptor-dependent gene expression. The Journal of biological chemistry. 265 [PubMed]

Almås B, Le Bourdelles B, Flatmark T, Mallet J, Haavik J. (1992). Regulation of recombinant human tyrosine hydroxylase isozymes by catecholamine binding and phosphorylation. Structure/activity studies and mechanistic implications. European journal of biochemistry. 209 [PubMed]

Barbeau A. (1968). Dopamine and dopamine metabolites in Parkinson's disease-a review. Proceedings of the Australian Association of Neurologists. 5 [PubMed]

Bartzokis G, Tishler TA, Shin IS, Lu PH, Cummings JL. (2004). Brain ferritin iron as a risk factor for age at onset in neurodegenerative diseases. Annals of the New York Academy of Sciences. 1012 [PubMed]

Benavides-Piccione R, DeFelipe J. (2003). Different populations of tyrosine-hydroxylase-immunoreactive neurons defined by differential expression of nitric oxide synthase in the human temporal cortex. Cerebral cortex (New York, N.Y. : 1991). 13 [PubMed]

Berresheim U, Kuhn DM. (1994). Dephosphorylation of tyrosine hydroxylase by brain protein phosphatases: a predominant role for type 2A. Brain research. 637 [PubMed]

Bertoldi M, Borri Voltattorni C. (2000). Reaction of dopa decarboxylase with L-aromatic amino acids under aerobic and anaerobic conditions. The Biochemical journal. 352 Pt 2 [PubMed]

Bevilaqua LR, Graham ME, Dunkley PR, von Nagy-Felsobuki EI, Dickson PW. (2001). Phosphorylation of Ser(19) alters the conformation of tyrosine hydroxylase to increase the rate of phosphorylation of Ser(40). The Journal of biological chemistry. 276 [PubMed]

Black BC, Smarrelli J. (1986). A kinetic analysis of Drosophila melanogaster dopa decarboxylase. Biochimica et biophysica acta. 870 [PubMed]

Charvin D, Vanhoutte P, Pagès C, Borrelli E, Caboche J. (2005). Unraveling a role for dopamine in Huntington's disease: the dual role of reactive oxygen species and D2 receptor stimulation. Proceedings of the National Academy of Sciences of the United States of America. 102 [PubMed]

Cho S, Neff NH, Hadjiconstantinou M. (1997). Regulation of tyrosine hydroxylase and aromatic L-amino acid decarboxylase by dopaminergic drugs. European journal of pharmacology. 323 [PubMed]

Clardy SL, Earley CJ, Allen RP, Beard JL, Connor JR. (2006). Ferritin subunits in CSF are decreased in restless legs syndrome. The Journal of laboratory and clinical medicine. 147 [PubMed]

Costello DJ, Walsh SL, Harrington HJ, Walsh CH. (2004). Concurrent hereditary haemochromatosis and idiopathic Parkinson's disease: a case report series. Journal of neurology, neurosurgery, and psychiatry. 75 [PubMed]

Daubner SC, Fitzpatrick PF. (1993). Alleviation of catecholamine inhibition of tyrosine hydroxylase by phosphorylation at serine40. Advances in experimental medicine and biology. 338 [PubMed]

Dekker MC et al. (2003). Mutations in the hemochromatosis gene (HFE), Parkinson's disease and parkinsonism. Neuroscience letters. 348 [PubMed]

Demarquay G et al. (2000). Clinical report of three patients with hereditary hemochromatosis and movement disorders. Movement disorders : official journal of the Movement Disorder Society. 15 [PubMed]

Dunkley PR, Bobrovskaya L, Graham ME, von Nagy-Felsobuki EI, Dickson PW. (2004). Tyrosine hydroxylase phosphorylation: regulation and consequences. Journal of neurochemistry. 91 [PubMed]

Faurbye A. (1968). The role of amines in the etiology of schizophrenia. Comprehensive psychiatry. 9 [PubMed]

Fitzpatrick PF. (1989). The metal requirement of rat tyrosine hydroxylase. Biochemical and biophysical research communications. 161 [PubMed]

Fitzpatrick PF. (1991). Steady-state kinetic mechanism of rat tyrosine hydroxylase. Biochemistry. 30 [PubMed]

Fitzpatrick PF. (1993). Mechanistic studies of tyrosine hydroxylase. Advances in experimental medicine and biology. 338 [PubMed]

Flatmark T et al. (1999). Tyrosine hydroxylase binds tetrahydrobiopterin cofactor with negative cooperativity, as shown by kinetic analyses and surface plasmon resonance detection. European journal of biochemistry. 262 [PubMed]

Flatmark T, Haavik J, Andersson KK, Cox DD, Que L. (1988). Resonance Raman studies on the blue-green-colored bovine adrenal tyrosine 3-monooxygenase (tyrosine hydroxylase). Evidence that the feedback inhibitors adrenaline and noradrenaline are coordinated to iron. J Biol Chem. 263

Frantom PA, Seravalli J, Ragsdale SW, Fitzpatrick PF. (2006). Reduction and oxidation of the active site iron in tyrosine hydroxylase: kinetics and specificity. Biochemistry. 45 [PubMed]

Fujisawa H, Okuno S. (1989). Regulation of the activity of tyrosine hydroxylase in the central nervous system. Advances in enzyme regulation. 28 [PubMed]

Fujisawa H, Okuno S. (2005). Regulatory mechanism of tyrosine hydroxylase activity. Biochemical and biophysical research communications. 338 [PubMed]

Fuller RW, Steinberg M. (1976). Regulation of enzymes that synthesize neurotransmitter monoamines. Advances in enzyme regulation. 14 [PubMed]

Funakoshi H, Okuno S, Fujisawa H. (1991). Different effects on activity caused by phosphorylation of tyrosine hydroxylase at serine 40 by three multifunctional protein kinases. The Journal of biological chemistry. 266 [PubMed]

GREER M, WILLIAMS CM. (1963). Dopamine metabolism in Parkinson's disease. Neurology. 13 [PubMed]

Gerlach J, Reisby N, Randrup A. (1974). Dopaminergic hypersensitivity and cholinergic hypofunction in the pathophysiology of tardive dyskinesia. Psychopharmacologia. 34 [PubMed]

Goldstein M. (1984). Regulatory mechanisms of dopamine biosynthesis at the tyrosine hydroxylase step. Annals of the New York Academy of Sciences. 430 [PubMed]

Golub MS et al. (2005). Movement disorders in the Hfe knockout mouse. Nutritional neuroscience. 8 [PubMed]

Haavik J, Andersson KK, Petersson L, Flatmark T. (1988). Soluble tyrosine hydroxylase (tyrosine 3-monooxygenase) from bovine adrenal medulla: large-scale purification and physicochemical properties. Biochimica et biophysica acta. 953 [PubMed]

Haavik J et al. (1989). Identification of protein phosphatase 2A as the major tyrosine hydroxylase phosphatase in adrenal medulla and corpus striatum: evidence from the effects of okadaic acid. FEBS letters. 251 [PubMed]

Haavik J, Toska K. (1998). Tyrosine hydroxylase and Parkinson's disease. Molecular neurobiology. 16 [PubMed]

Hairer E, Wanner G. (1999). Stiff differential equations solved by Radau methods J Comput Appl Math. 111

Harada T, Kagamiyama H, Hatakeyama K. (1993). Feedback regulation mechanisms for the control of GTP cyclohydrolase I activity. Science (New York, N.Y.). 260 [PubMed]

Harris JE, Morgenroth VH, Roth RH, Baldessarini RJ. (1974). Regulation of catecholamine synthesis in the rat brain in vitro by cyclic AMP. Nature. 252 [PubMed]

Haycock JW, Ahn NG, Cobb MH, Krebs EG. (1992). ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ. Proceedings of the National Academy of Sciences of the United States of America. 89 [PubMed]

He X, Lee KY, Li Lh LH, Meller E, Goldstein M. (1996). Relationship between Enzymatic Activity and Oligomerization State of Tyrosine Hydroxylase. Journal of biomedical science. 3 [PubMed]

Hornykiewicz O. (1975). Brain monoamines and parkinsonism. Natl Inst Drug Abuse Res Monogr Ser. 3

Ikeda M, Fahien LA, Udenfriend S. (1966). A kinetic study of bovine adrenal tyrosine hydroxylase. The Journal of biological chemistry. 241 [PubMed]

Joh TH, Park DH, Reis DJ. (1978). Direct phosphorylation of brain tyrosine hydroxylase by cyclic AMP-dependent protein kinase: mechanism of enzyme activation. Proceedings of the National Academy of Sciences of the United States of America. 75 [PubMed]

Justice JB, Nicolaysen LC, Michael AC. (1988). Modeling the dopaminergic nerve terminal. Journal of neuroscience methods. 22 [PubMed]

Kappock TJ, Caradonna JP. (1996). Pterin-Dependent Amino Acid Hydroxylases. Chemical reviews. 96 [PubMed]

Kish SJ et al. (2001). Striatal dopaminergic and serotonergic markers in human heroin users. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 24 [PubMed]

Kuczenski RT, Mandell AJ. (1972). Regulatory properties of soluble and particulate rat brain tyrosine hydroxylase. The Journal of biological chemistry. 247 [PubMed]

Kung L, Force M, Chute DJ, Roberts RC. (1998). Immunocytochemical localization of tyrosine hydroxylase in the human striatum: a postmortem ultrastructural study. The Journal of comparative neurology. 390 [PubMed]

Lazar MA, Lockfeld AJ, Truscott RJ, Barchas JD. (1982). Tyrosine hydroxylase from bovine striatum: catalytic properties of the phosphorylated and nonphosphorylated forms of the purified enzyme. Journal of neurochemistry. 39 [PubMed]

Lazar MA, Mefford IN, Barchas JD. (1982). Tyrosine hydroxylase activation. Comparison of in vitro phosphorylation and in vivo administration of haloperidol. Biochemical pharmacology. 31 [PubMed]

Le Bourdellès B et al. (1991). Phosphorylation of human recombinant tyrosine hydroxylase isoforms 1 and 2: an additional phosphorylated residue in isoform 2, generated through alternative splicing. The Journal of biological chemistry. 266 [PubMed]

Leal RB, Sim AT, Gonçalves CA, Dunkley PR. (2002). Tyrosine hydroxylase dephosphorylation by protein phosphatase 2A in bovine adrenal chromaffin cells. Neurochemical research. 27 [PubMed]

MONOD J, WYMAN J, CHANGEUX JP. (1965). ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL. Journal of molecular biology. 12 [PubMed]

Margolese HC, Chouinard G, Kolivakis TT, Beauclair L, Miller R. (2005). Tardive dyskinesia in the era of typical and atypical antipsychotics. Part 1: pathophysiology and mechanisms of induction. Canadian journal of psychiatry. Revue canadienne de psychiatrie. 50 [PubMed]

Mineyeva MF, Kudrin VS, Rayevsky KS. (1978). Brain tyrosine hydroxylase: kinetic properties and regulation of the activity. Annali dell'Istituto superiore di sanita. 14 [PubMed]

Mogi M et al. (1988). Homospecific activity (activity per enzyme protein) of tyrosine hydroxylase increases in parkinsonian brain. Journal of neural transmission. 72 [PubMed]

Morgenroth VH, Hegstrand LR, Roth RH, Greengard P. (1975). Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase. The Journal of biological chemistry. 250 [PubMed]

Nishimura M, Uyeda K. (1995). Purification and characterization of a novel xylulose 5-phosphate-activated protein phosphatase catalyzing dephosphorylation of fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase. The Journal of biological chemistry. 270 [PubMed]

Oka K, Kato T, Sugimoto T, Matsuura S, Nagatsu T. (1981). Kinetic properties of tyrosine hydroxylase with natural tetrahydrobiopterin as cofactor. Biochimica et biophysica acta. 661 [PubMed]

Olefirowicz TM, Ewing AG. (1990). Dopamine concentration in the cytoplasmic compartment of single neurons determined by capillary electrophoresis. Journal of neuroscience methods. 34 [PubMed]

Peng X, Tehranian R, Dietrich P, Stefanis L, Perez RG. (2005). Alpha-synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells. Journal of cell science. 118 [PubMed]

Perlman RL, Sheard BE. (1982). Estimation of the cytoplasmic catecholamine concentrations in pheochromocytoma cells. Biochimica et biophysica acta. 719 [PubMed]

Pickel VM, Beckley SC, Joh TH, Reis DJ. (1981). Ultrastructural immunocytochemical localization of tyrosine hydroxylase in the neostriatum. Brain research. 225 [PubMed]

Quinsey NS, Luong AQ, Dickson PW. (1998). Mutational analysis of substrate inhibition in tyrosine hydroxylase. Journal of neurochemistry. 71 [PubMed]

Ramsey AJ, Fitzpatrick PF. (1998). Effects of phosphorylation of serine 40 of tyrosine hydroxylase on binding of catecholamines: evidence for a novel regulatory mechanism. Biochemistry. 37 [PubMed]

Ramsey AJ, Fitzpatrick PF. (2000). Effects of phosphorylation on binding of catecholamines to tyrosine hydroxylase: specificity and thermodynamics. Biochemistry. 39 [PubMed]

Ramsey AJ, Hillas PJ, Fitzpatrick PF. (1996). Characterization of the active site iron in tyrosine hydroxylase. Redox states of the iron. The Journal of biological chemistry. 271 [PubMed]

Rausch WD, Hirata Y, Nagatsu T, Riederer P, Jellinger K. (1988). Tyrosine hydroxylase activity in caudate nucleus from Parkinson's disease: effects of iron and phosphorylating agents. Journal of neurochemistry. 50 [PubMed]

Reith J et al. (1994). Elevated dopa decarboxylase activity in living brain of patients with psychosis. Proceedings of the National Academy of Sciences of the United States of America. 91 [PubMed]

Richtand NM, Inagami T, Misono K, Kuczenski R. (1985). Purification and characterization of rat striatal tyrosine hydroxylase. Comparison of the activation by cyclic AMP-dependent phosphorylation and by other effectors. The Journal of biological chemistry. 260 [PubMed]

Roskoski R, Roskoski LM. (1987). Activation of tyrosine hydroxylase in PC12 cells by the cyclic GMP and cyclic AMP second messenger systems. Journal of neurochemistry. 48 [PubMed]

Royo M, Fitzpatrick PF, Daubner SC. (2005). Mutation of regulatory serines of rat tyrosine hydroxylase to glutamate: effects on enzyme stability and activity. Archives of biochemistry and biophysics. 434 [PubMed]

Salvatore MF, Waymire JC, Haycock JW. (2001). Depolarization-stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ. Journal of neurochemistry. 79 [PubMed]

Sloane RB, Hughes W, Haust HL. (1966). Catechloamine excretion in manic-depressive and schizophrenic psychosis and its relationship to symptomatology. Canadian Psychiatric Association journal. 11 [PubMed]

Takahashi R et al. (1968). Catecholamine metabolism of manic-depressive illness. Journal of psychiatric research. 6 [PubMed]

Thibault J et al. (1992). Purification and characterization of the blue-green rat phaeochromocytoma (PC12) tyrosine hydroxylase with a dopamine-Fe(III) complex. Reversal of the endogenous feedback inhibition by phosphorylation of serine-40. Biochem J. 284 ( Pt 3)

Trottier S, Geffard M, Evrard B. (1989). Co-localization of tyrosine hydroxylase and GABA immunoreactivities in human cortical neurons. Neuroscience letters. 106 [PubMed]

Vulliet PR, Langan TA, Weiner N. (1980). Tyrosine hydroxylase: a substrate of cyclic AMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 77 [PubMed]

Vulliet PR, Woodgett JR, Cohen P. (1984). Phosphorylation of tyrosine hydroxylase by calmodulin-dependent multiprotein kinase. The Journal of biological chemistry. 259 [PubMed]

Vulliet PR, Woodgett JR, Ferrari S, Hardie DG. (1985). Characterization of the sites phosphorylated on tyrosine hydroxylase by Ca2+ and phospholipid-dependent protein kinase, calmodulin-dependent multiprotein kinase and cyclic AMP-dependent protein kinase. FEBS letters. 182 [PubMed]

Wagner AF et al. (1966). A further study of catecholamine omicron-methylation in schizophrenia. Nature. 211 [PubMed]

Wolozin B, Golts N. (2002). Iron and Parkinson's disease. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 8 [PubMed]

Yamauchi T, Nakata H, Fujisawa H. (1981). A new activator protein that activates tryptophan 5-monooxygenase and tyrosine 3-monooxygenase in the presence of Ca2+-, calmodulin-dependent protein kinase. Purification and characterization. The Journal of biological chemistry. 256 [PubMed]

Zigmond MJ, Perez RG, Hastings TG. (2002). Increased dopamine turnover after partial loss of dopaminergic neurons: compensation or toxicity? Parkinsonism Relat Disord. 8