CA1 stratum radiatum interneuron multicompartmental model (Katona et al. 2011)

The model examines dendritic NMDA-spike generation and propagation in the dendrites of CA1 stratum radiatum interneurons. It contains NMDA-channels in a clustered pattern on a dendrite and K-channels. The simulation shows the whole NMDA spike and the rising phase of the traces in separate windows.

Model Type: Neuron or other electrically excitable cell

Region(s) or Organism(s): Hippocampus

Cell Type(s): Hippocampus CA1 stratum radiatum interneuron

Currents: I Na,t; I K

Receptors: NMDA

Model Concept(s): Action Potential Initiation; Dendritic Action Potentials; Active Dendrites; Detailed Neuronal Models

Simulation Environment: NEURON

Implementer(s): Rozsa, Balazs

References:

Katona G et al. (2011). Roller Coaster Scanning reveals spontaneous triggering of dendritic spikes in CA1 interneurons. Proceedings of the National Academy of Sciences of the United States of America. 108 [PubMed]