Dendritic Discrimination of Temporal Input Sequences (Branco et al. 2010)

Compartmental model of a layer 2/3 pyramidal cell in the rat somatosensory cortex, exploring NMDA-dependent sensitivity to the temporal sequence of synaptic activation.

Model Type: Neuron or other electrically excitable cell; Dendrite

Region(s) or Organism(s): Neocortex

Cell Type(s): Neocortex L2/3 pyramidal GLU cell

Receptors: NMDA

Transmitters: Glutamate

Model Concept(s): Spatio-temporal Activity Patterns; Synaptic Integration; Direction Selectivity

Simulation Environment: NEURON


Branco T, Clark BA, Häusser M. (2010). Dendritic discrimination of temporal input sequences in cortical neurons. Science (New York, N.Y.) 329 [PubMed]

Branco T, Häusser M. (2011). Synaptic integration gradients in single cortical pyramidal cell dendrites. Neuron 69 [PubMed]